Kentucky native Jess Walker's big-city career has kept her too busy to visit her sisters and hometown. However, she relents when she's invited to celebrate her nephew's third birthday at the newly established Three Sisters B&B in the heart of bourbon country. The nostalgic bubble is quickly popped however when Jess realizes her family hasn't been entirely honest with her. She was invited not so much for a family reunion, but to help them impress some VIP guests for inclusion in a tourism co-op on the bourbon trail.
Old resentments arise, and the sisters are at loggerheads immediately. But when one of the VIP guests is found dead, things only get worse. The sheriff is intent on treating the death as an accident, blaming it on unsafe conditions at the B&B. But the sisters know this was murder. Jess has always been the fixer of the family, so she jumps in to protect her sisters and their B&B's reputation. With the remaining guests and the attractive—and single—owner of the nearby whiskey barrel factory all suspects, Jess has her work cut out for her. And it turns out, she can't do it alone. All three sisters will need to work in perfect harmony in order to find the perpetrator of the Old Kentucky Homicide.